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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '887b735a2eaef13565e5ec6ec1f1d19c3910f6a996c5c1665f99537dcceb23a8' 
  AND token = '8xL75fEVNomGkgLPpKTM7yMle4PLu+VmoRrXawz6PpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}