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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb4d8a7f711b0720d37022582efe7c1fb978f33f3e357be49ef0e7b4d1d036f4' 
  AND token = 'FJTOPCZOgnGVuRHWy5xs+AnYay/9ZXVyHGWI8d1xJr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}