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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d4111011e60c053d26599507c4ec953c40dd941070a30109c93233d7d59397' 
  AND token = 'tBuWfjCBAeIUIMhGg8YsW7rctDoQpkJalP2cH9P+XC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}