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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6f59e2ef7aaba18e5f771477b51eda00120fa3c2b7a5a76720d6f15d42f266' 
  AND token = 'UiyrZxbKmbd+b9F8HDGOa7EMRvEh02ekk0uVLRoC/U0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}