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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9eb1d02b967ab9b2f359bfa426cd1708953c81e7dfb64d7778d4764019f469a0' 
  AND token = '+fkxUPiOe/iV7Aer2tSBix7fmiNYZVjOhL3/LRIe5dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}