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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46f6f5ec3cbad2885e5fe3742560267f86a21301b852e04f08d74df568a1cd49' 
  AND token = '2pcMCvCsZEoIrBNJW1Qz2zE2E67h3XtKVkiDjQdts3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}