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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de1b9ed321fc56b1e3b4b5922330f6118a32e63529ad7772cc2294cb9758995' 
  AND token = '0ajx1rJIqXDFbAGYP5rl9gUI4ebYHVvA/yX0lyyZ7Pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}