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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c148b0f3ff0ed05e29ccaf5e063b31320fbf507685a7c7bf64d86599b77b42aa' 
  AND token = 'CTQnPpA5f7xzjXxZi9xlPf5BNYALkuL0D/kU5LLZUS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}