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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a2cfe22217f7e5f04d7ac12236409fede74d597f5f5443a23b26f79f9ef5af' 
  AND token = 'lFdyiN8aylXp6jgxduJ/Mu+4MhVJDZS9KIPyWEo90Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}