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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2c6540133689217a0a4bab0eaef3188b32532e84b5dfae0ac303be173229535' 
  AND token = 'QbrjQYs/+N4Mo7fBKGLp8vkDv+MM9wWxv9x/yCDiSis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}