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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67ae455432b6a7cce6aaa44f85280776b3e6322003a7032c4f22f20ef3c305a4' 
  AND token = '/kxJXAsem/W9GxRaRIysK7NJU4iSEzMW2/Y3lrbRcRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}