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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48472fb8150986ef69f80c34dc197d52226506b540438fffb83595be7aad876d' 
  AND token = 'XfHuYsPi0rvHmU6seEdkXBOXRtVOd7S03x1B2dwSPgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}