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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c0b2e4982366dd585dc786110011e1f1e10129fb1f5db08c3f38280adae43c' 
  AND token = '1LYfofPVkrc5O4zUry0afZUDSH4T6qRThEW0fB7tKms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}