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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de046aba133a5e668f3137f02c3eb0cb3595d9e3a4050be7da6c5d6da25bf451' 
  AND token = 'oAO7Nu3icOYpm1Qodtxp9boFcRq6pFZtSbSOIpTA83A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}