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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e51df05af0a121b29cbdb35316290801cb6e9aa8caf9dbf8f9600de105a41b8' 
  AND token = '/69f5b0tEWg1aFC29JS/8KPoMWSQbWjK7T1FoFE6hJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}