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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6fe8944a7ec635569e0af2589a76336e916ac817c57859c9ddc74fd3a9fbd80' 
  AND token = 'XYWjVqEa0Q/k3NXDNdjJE+Za3YOfox1LVHQAcQxbbXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}