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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffb0c602c3b83e3d50365ddbe50256769aa1faa0054133e25cee935287e12521' 
  AND token = 'gYnAcHLm7NMEzGiBHpLhfC4Mk/soEfsKiPAJTTgPKCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}