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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7efe0c3bda16b4b83f2baf7d34d2f869c0c5545244abfdfd9ccc218dd6c52c' 
  AND token = 'xRBS6E6KFeXcrS4aErAbHhshR3x13FjM/OLJswUSQd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}