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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d2c88efc8243454a8c1a6f5ed7fbd40afc20ab14681504f2278c65ae7643da' 
  AND token = 'umi25O2wp/DajPDjUhH7ZWu5EM3vhHWR5Gf3rjNBNV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}