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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bc4f4a94567520d46c1ca3424a99eda53e442a96954f4dea2642e7a94df4278' 
  AND token = 'kb0SipgJ/EeX65fiET6pWIAXftIyVqM+VuhB8KTsksQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}