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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d460711cc84216cea9ab7085de902db07cd7465a6c7eebceb775eb3b7f1bcb7' 
  AND token = 'DfQK2WDK15XbaZWRlLEqp1nhbCeW5daOQrKj+r8V0z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}