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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b54992cd03b999b3aeb7d201c0c914f9a757cecef00344718fdd5c8ee25fc9b6' 
  AND token = 'Mpi9mPBD3vxENRwfzbDdN3ty6ADzx+o74gC+PgF3wGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}