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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6fb19a5bf29960705c1153a64f24a86d6075c14b0714dfdf11ace29e2267ff5' 
  AND token = 'a/M5KYcLegKsb1wy+EOReyyTKDf3M0cVujIJFXdQnbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}