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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2f932303ea0f76ee12238672cceaac40bbb5bf8ce9ce2a165bf0f8d5c059eac' 
  AND token = 'O2HDeOxL691Tuy7A8O7vboeqwkptURagLlTB4D15/Xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}