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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3b2bd9b846e1c5079edf2543a304b435b5a9f0d009044e20050ff0806e5e407' 
  AND token = 'TeRBYvZtBqbifj2B1tzuo+HnR8IfH6T8RW7mny6iZrs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}