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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f3a322f7f9e8b80eae50da08509e91c1350bb02709155083c301fce034ed7c4' 
  AND token = 'I+dzIZMnSN54OoqaPkwv+6uAlUZvMMwUYfv1H9ZqopI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}