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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fb9cc7d0dd1ac0e0dc83daaf1e888c9fdc899a3e6144cb291ecb1f0565b8f9c' 
  AND token = 'ADmY8KqeEc0nci/pUNhe8ae460FOeyT2d2bNNN5zWic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}