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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ade15a5c51b910e501f8e3f2212cbeffcaf5aefe8873e98177314596da3cc09' 
  AND token = 'XKbUwQ8q6ULz+bfhGo0D1Wlv5CQZYnUFk4/NGxMEa6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}