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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fceedce822f02646e5a10b5e28054ebe4505806aefb1108cc18ab31aa215064' 
  AND token = '8LX/TLEItCA2pZHMrFysJ1skntpNF6BAcEOxsOkZjzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}