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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '649c13423cb20c6dde0b16a9c99e85c9a1ca6060fb4a4cc6ab3c9ce44b025da9' 
  AND token = 'M2K2MBAyb+hGgsJ9LIjDOUJy2EK6qyXVCyU1C7OOXew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}