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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f385308ee9a6ef8203dfb83aa1ff29e57defa95c726991c7947db81f137bac96' 
  AND token = '3xygXC9zRMS03HC7ydUSg+40RDSxZ23czslEHtK7lYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}