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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1129bdff0cf19dcaee06a0bad63f85a42ba6a66c4798e136c65143e194216f09' 
  AND token = 'Z9StfbkedOz6cTwS8r4SZr2nlLR08L9WDy6EOY+w3Ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}