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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e48b8df82056e3dbb8af2f170088fdbcd03937cf096fb24f3d839d54ef5d25e' 
  AND token = 'AVBJ2YV+nZT0gPyM0B0U9h1HOG0kH4Gg3gYTC+ctwng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}