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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e604015d863e4b2709fee398342980e8a58137404238090601a154c22ce0e00' 
  AND token = 'VPMoqsC8IbNge00nQB2gQqoG/XPflwAAfr3wOiCaj9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}