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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d4460a0dcddca717a5fd117898ab3d1553ea126bde91caad44a47eac627b74e' 
  AND token = 'xQWc1BZK+CkBo164fgiy53AUldTLBaMzkz+UWnVaJAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}