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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3206ad1f01bc189c4a4a88165cc064b3a8ad874cb71ba5801e1699bc10cc780' 
  AND token = 'AAticKuBI2vDAuL12icLtgRMxVnMev3TiYzPvUCfnOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}