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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca0528e784e62f04b1d430dae387797b636a08649c03e40a4d4b9354739bb85c' 
  AND token = '326H3UTjF5n7dSaHgFmCB3avA29+JpXDS9l19vd3Ies=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}