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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f5069818aa85054078b7a7b7baa20339a56815099f05741b5a604e49a9e05b3' 
  AND token = 'md4wtT6juVSiVAh4tJqKAI2bDMFwXSH8QEkpFVOSkGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}