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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f61e60d9d557eee23d177f435b7f3188566e10425d982535e58c813bdcbe72f7' 
  AND token = 'CebTJ+7BHQoCEnAxZzpcLvZ22PoCcvMH6eXjNQvFxcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}