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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c647641133cc0f12713ddd3c7b44d4378f288c8728f743c30e39d14bb4f441' 
  AND token = 'Yqbiv88bhhBZ55Si5Y+d8WlwLahb5Y71Q61RI/+sbtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}