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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e744b75ce31209658bb81e50d7509ed9b23e84a5847c55c501576324ee7a5b6' 
  AND token = 'HO+bGvirVymYk1DrovHcIineI21qXAhOZqCPAxLahSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}