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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0565ce7c9846f740bf3d81b644f936cbcf1d00773ab0f67105c87b6d75f13c6' 
  AND token = 'gG/A63EHlnN+Lalr8Yq2S/2Xza1QeRAg2DkC84Y7FVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00071

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}