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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e43024ae627dd80d59ee3bfad10164d119fa7806f13249dc88de31b1b42b5b9' 
  AND token = 'djtecTBG6b+bY6aSzCphxBIrAdp1c0iQ35vAHJMbFkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}