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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2645cc84f6d9ab6256df778343b92355bbc6915c8a6ee60b2390b259a91518a5' 
  AND token = 'XXM9UHD135ew3rE6wufmhexQ5lKKOZnjqlXxICrP0t4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}