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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6918870e082ac161e518c369facfbb29701038e7cf27a221c7bf9fe127a81f6c' 
  AND token = '0JrxMvgwxlXpODmtyYUuoDDzVRsMfh1k92JKzy48V4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}