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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1966df1fec844870cae1769472cc1f870fcc51564552f82e594e0ec2529a3fe' 
  AND token = 'jhYPs1xaLiR4wBW679fhNxdctWdlfrCDV4Y+OOZQ8i8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}