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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a23a602c28c5dfca2d51bc57ef09e0db650bdfd0be60681c8bc24cd540f5c75' 
  AND token = '8MurJvZp9s+W8ySagsMTo9Nj3cm3fhJD2PXLWZcd9Ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}