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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53ae8105aacbdfef3eff79f031dd7ac3512708b92e4aede37704786fec4f521' 
  AND token = 're4TIenuHe1k1PK5fqjvbIB8tYZmdkeIIKeG5NqvB8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}