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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9648c9364816dd9660f3f6fe66619dea504bbb9ef02246e8cfeeb36fc9129448' 
  AND token = 'z6937T47Ld8t6GKxFps5JvGPN+Fl1V9VcuICGIF+zkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}