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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '812b265aa27c8b11b17ebbc9f267c2464e9e165ab8c9398d8828d5f1e7642960' 
  AND token = 'C5o0uOPSSUNump0mcmXL3QOtmkxK72vtKdBtTnESg94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}